What is diabetic polyneuropathy?
Diabetic polyneuropathy (DPN) affects multiple peripheral sensory and motor nerves that branch out from the spinal cord into the arms, hands, legs and feet. Typically, the longest nerves — those that extend from the spine to the feet — are affected the most.
What is the pathophysiology of diabetic neuropathy?
The pathophysiology of diabetic peripheral neuropathy is multifactorial and is thought to result from vascular disease occluding the vasa nervorum; endothelial dysfunction; deficiency of myoinositol-altering myelin synthesis and diminishing sodium-potassium adenine triphosphatase (ATPase) activity; chronic …
What is the most common type of diabetic neuropathy?
Peripheral neuropathy is the most common form of diabetic neuropathy. Your feet and legs are often affected first, followed by your hands and arms. Possible signs and symptoms of peripheral neuropathy include: Numbness or reduced ability to feel pain or changes in temperature, especially in your feet and toes.
What kind of pain is diabetic neuropathy?
Patients with painful diabetic neuropathy characteristically present with tingling sensation, numbness, burning, excruciating stabbing type of pain, sometimes intractable and may be associated with paraesthesia and hyperesthesia coupled with deep aching in feet or hands.
Is polyneuropathy the same as neuropathy?
Polyneuropathy is when multiple peripheral nerves become damaged, which is also commonly called peripheral neuropathy.
What are the three types of neuropathy?
Peripheral Neuropathy Types
- Motor neuropathy. This is damage to the nerves that control muscles and movement in the body, such as moving your hands and arms or talking.
- Sensory neuropathy.
- Autonomic nerve neuropathy.
- Combination neuropathies.
Is there a difference between diabetic neuropathy and peripheral neuropathy?
Peripheral neuropathy is nerve damage most often caused by diabetes, hence it is also referred to as diabetic peripheral neuropathy; it is a result of prolonged elevated levels of blood sugar.
What is an example of polyneuropathy?
Peripheral neuropathy can affect one nerve (mononeuropathy), two or more nerves in different areas (multiple mononeuropathy), or many nerves (polyneuropathy). Carpal tunnel syndrome is an example of mononeuropathy. Most people with peripheral neuropathy have polyneuropathy.
What is the difference between polyneuropathy and neuropathy?
Some forms of neuropathy involve damage to only one nerve (called mononeuropathy). Neuropathy affecting two or more nerves in different areas is called multiple mononeuropathy or mononeuropathy multiplex. More often, many or most of the nerves are affected (called polyneuropathy).
Is polyneuritis and polyneuropathy the same?
Classification of peripheral neuropathy, therefore, remains largely descriptive. The term polyneuritis (or polyneuropathy) refers to an illness marked by disordered function of several or many peripheral nerves. There is resultant motor weakness, sensory loss, and pain in varying proportions.
What is the difference between polyneuropathy and focused neuropathy?
All of the types of diabetic neuropathy above—peripheral, autonomic, and proximal—are examples of polyneuropathy. Poly means that they affect many nerves. Focal neuropathy, by contrast, affects one specific nerve; it’s focused neuropathy.
What is the relationship between diabetes and polyneuropathy?
It is the most common and often the first complication associated with diabetes. Polyneuropathy is also commonly associated with prediabetes, chemotherapy, alcoholism, HIV infection and advanced age. The mechanism by which peripheral neurons dysfunction in polyneuropathy is complex, multifactorial and the subject of ongoing research.
What is diabetic neuropathy and peripheral neuropathy?
Diabetic neuropathy is a dysfunction of nerve fibers in people with diabetes. When the peripheral nerve fibers are affected the condition is called peripheral neuropathy. What is Diabetic Neuropathy?
What is polypolyneuropathy?
Polyneuropathy is the most common type of peripheral neuropathy. It is a progressive length dependent dysfunction of the peripheral nervous system that usually starts in the great toes and ascends up the feet and legs over time in a stocking/glove distribution.